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N-(4-(2-(2-AMINO-3,4-DIHYDRO-4-OXO-7H-PYRROLO(2,3-D)PYRIMDIN-5-YL)ETHYL)BENZOYL)GLUTAMIC ACID
Descriptors Found:
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DeCS
Descriptor
English
:
Pemetrexed
Descriptor
Spanish
:
Pemetrexed
Descriptor
Portuguese
:
Pemetrexede
Synonyms
English
:
Alimta
LY 231,514
LY 231514
LY-231,514
LY-231514
LY231514
MTA
N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
Pemetrexed Disodium
231,514, LY
231514, LY
Disodium, Pemetrexed
Tree Number:
D03.633.100.759.758.399.454.650
D12.125.067.625.525
D12.125.119.409.525
Definition
English
:
A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of,
THYMIDYLATE SYNTHASE.
History Note
English
:
2016 (1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55935
Unique Identifier:
D000068437
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS